TAZ/Wnt-β-catenin/c-MYC axis regulates cystogenesis in polycystic kidney disease

Autosomal-dominant polycystic kidney disease (ADPKD) is the most common genetic renal disease, primarily caused by germline mutation of PKD1 or PKD2, leading to end-stage renal disease. The Hippo signaling pathway regulates organ growth and cell proliferation. Herein, we demonstrate the regulatory m...

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Detalles Bibliográficos
Autores principales: Lee, Eun Ji, Seo, Eunjeong, Kim, Jin Won, Nam, Sun Ah, Lee, Jong Young, Jun, Jaehee, Oh, Sumin, Park, Minah, Jho, Eek-hoon, Yoo, Kyung Hyun, Park, Jong Hoon, Kim, Yong Kyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682393/
https://www.ncbi.nlm.nih.gov/pubmed/33122431
http://dx.doi.org/10.1073/pnas.2009334117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682393/
https://www.ncbi.nlm.nih.gov/pubmed/33122431
http://dx.doi.org/10.1073/pnas.2009334117

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