The inhibition of LSD1 via sequestration contributes to tau-mediated neurodegeneration

Tauopathies are a class of neurodegenerative diseases associated with pathological tau. Despite many advances in our understanding of these diseases, the direct mechanism through which tau contributes to neurodegeneration remains poorly understood. Previously, our laboratory implicated the histone d...

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Detalles Bibliográficos
Autores principales: Engstrom, Amanda K., Walker, Alicia C., Moudgal, Rohitha A., Myrick, Dexter A., Kyle, Stephanie M., Bai, Yu, Rowley, M. Jordan, Katz, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682552/
https://www.ncbi.nlm.nih.gov/pubmed/33139560
http://dx.doi.org/10.1073/pnas.2013552117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682552/
https://www.ncbi.nlm.nih.gov/pubmed/33139560
http://dx.doi.org/10.1073/pnas.2013552117

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