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The inhibition of LSD1 via sequestration contributes to tau-mediated neurodegeneration
Tauopathies are a class of neurodegenerative diseases associated with pathological tau. Despite many advances in our understanding of these diseases, the direct mechanism through which tau contributes to neurodegeneration remains poorly understood. Previously, our laboratory implicated the histone d...
Autores principales: | Engstrom, Amanda K., Walker, Alicia C., Moudgal, Rohitha A., Myrick, Dexter A., Kyle, Stephanie M., Bai, Yu, Rowley, M. Jordan, Katz, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682552/ https://www.ncbi.nlm.nih.gov/pubmed/33139560 http://dx.doi.org/10.1073/pnas.2013552117 |
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