Optogenetic regulation of embryo implantation in mice using photoactivatable CRISPR-Cas9

Embryo implantation is achieved upon successful interaction between a fertilized egg and receptive endometrium and is mediated by spatiotemporal expression of implantation-associated molecules including leukemia inhibitory factor (LIF). Here we demonstrate, in mice, that LIF knockdown via a photoact...

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Detalles Bibliográficos
Autores principales: Takao, Tomoka, Sato, Moritoshi, Maruyama, Tetsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682590/
https://www.ncbi.nlm.nih.gov/pubmed/33139551
http://dx.doi.org/10.1073/pnas.2016850117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682590/
https://www.ncbi.nlm.nih.gov/pubmed/33139551
http://dx.doi.org/10.1073/pnas.2016850117

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