Hypoxic Tumor-Derived Exosomal Circ0048117 Facilitates M2 Macrophage Polarization Acting as miR-140 Sponge in Esophageal Squamous Cell Carcinoma

INTRODUCTION: Hypoxia and tumor-associated macrophage (TAM) are key regulators in remodeling the microenvironment of esophageal squamous cell carcinoma (ESCC). Hypoxia could stimulate tumor cells to secrete more exosomes and activate TAMs to M2 type. Here, we investigated the function and the underl...

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Detalles Bibliográficos
Autores principales: Lu, Qijue, Wang, Xinyu, Zhu, Ji, Fei, Xiang, Chen, Hezhong, Li, Chunguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682796/
https://www.ncbi.nlm.nih.gov/pubmed/33239890
http://dx.doi.org/10.2147/OTT.S284192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682796/
https://www.ncbi.nlm.nih.gov/pubmed/33239890
http://dx.doi.org/10.2147/OTT.S284192

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