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Two-step multi-omics modelling of drug sensitivity in cancer cell lines to identify driving mechanisms

Drug sensitivity prediction models for human cancer cell lines constitute important tools in identifying potential computational biomarkers for responsiveness in a pre-clinical setting. Integrating information derived from a range of heterogeneous data is crucial, but remains non-trivial, as differe...

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Detalles Bibliográficos
Autores principales: Kusch, Nina, Schuppert, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682852/
https://www.ncbi.nlm.nih.gov/pubmed/33226984
http://dx.doi.org/10.1371/journal.pone.0238961