Cargando…
Using B cell receptor lineage structures to predict affinity
We are frequently faced with a large collection of antibodies, and want to select those with highest affinity for their cognate antigen. When developing a first-line therapeutic for a novel pathogen, for instance, we might look for such antibodies in patients that have recovered. There exist effecti...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682889/ https://www.ncbi.nlm.nih.gov/pubmed/33175831 http://dx.doi.org/10.1371/journal.pcbi.1008391 |