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Natural variation in the sequestosome-related gene, sqst-5, underlies zinc homeostasis in Caenorhabditis elegans

Zinc is an essential trace element that acts as a co-factor for many enzymes and transcription factors required for cellular growth and development. Altering intracellular zinc levels can produce dramatic effects ranging from cell proliferation to cell death. To avoid such fates, cells have evolved...

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Detalles Bibliográficos
Autores principales: Evans, Kathryn S., Zdraljevic, Stefan, Stevens, Lewis, Collins, Kimberly, Tanny, Robyn E., Andersen, Erik C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682890/
https://www.ncbi.nlm.nih.gov/pubmed/33175833
http://dx.doi.org/10.1371/journal.pgen.1008986