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Self-complementarity in adeno-associated virus enhances transduction and gene expression in mouse cochlear tissues

Sensorineural hearing loss is one of the most common disabilities worldwide. Such prevalence necessitates effective tools for studying the molecular workings of cochlear cells. One prominent and effective vector for expressing genes of interest in research models is adeno-associated virus (AAV). How...

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Detalles Bibliográficos
Autores principales: Casey, Graham, Askew, Charles, Brimble, Mark A., Samulski, R. Jude, Davidoff, Andrew M., Li, Chengwen, Walters, Bradley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682903/
https://www.ncbi.nlm.nih.gov/pubmed/33227033
http://dx.doi.org/10.1371/journal.pone.0242599