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Large domain movements through the lipid bilayer mediate substrate release and inhibition of glutamate transporters
Glutamate transporters are essential players in glutamatergic neurotransmission in the brain, where they maintain extracellular glutamate below cytotoxic levels and allow for rounds of transmission. The structural bases of their function are well established, particularly within a model archaeal hom...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7682989/ https://www.ncbi.nlm.nih.gov/pubmed/33155546 http://dx.doi.org/10.7554/eLife.58417 |