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Allelic Distribution of Genes for Apolipoprotein E and MTHFR in Patients with Alzheimer’s Disease and Their Epistatic Interaction

BACKGROUND: Genetic risk factors play an important role in the pathogenesis of Alzheimer’s disease (AD). However, the gene-gene interaction (epistasis) between specific allelic variants is only partially understood. OBJECTIVE: In our study, we examined the presence of the ɛ4 allele of apolipoprotein...

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Detalles Bibliográficos
Autores principales: Sutovsky, Stanislav, Petrovic, Robert, Fischerova, Maria, Haverlikova, Viera, Ukropcova, Barbara, Ukropec, Jozef, Turcani, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683064/
https://www.ncbi.nlm.nih.gov/pubmed/32804129
http://dx.doi.org/10.3233/JAD-200321