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Allelic Distribution of Genes for Apolipoprotein E and MTHFR in Patients with Alzheimer’s Disease and Their Epistatic Interaction
BACKGROUND: Genetic risk factors play an important role in the pathogenesis of Alzheimer’s disease (AD). However, the gene-gene interaction (epistasis) between specific allelic variants is only partially understood. OBJECTIVE: In our study, we examined the presence of the ɛ4 allele of apolipoprotein...
Autores principales: | Sutovsky, Stanislav, Petrovic, Robert, Fischerova, Maria, Haverlikova, Viera, Ukropcova, Barbara, Ukropec, Jozef, Turcani, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683064/ https://www.ncbi.nlm.nih.gov/pubmed/32804129 http://dx.doi.org/10.3233/JAD-200321 |
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