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Oxidative Stress in Amyotrophic Lateral Sclerosis: Pathophysiology and Opportunities for Pharmacological Intervention

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease or Charcot disease, is a fatal neurodegenerative disease that affects motor neurons (MNs) and leads to death within 2–5 years of diagnosis, without any effective therapy available. Although the pathological mechanisms leadi...

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Detalles Bibliográficos
Autores principales: Cunha-Oliveira, Teresa, Montezinho, Liliana, Mendes, Catarina, Firuzi, Omidreza, Saso, Luciano, Oliveira, Paulo J., Silva, Filomena S. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683149/
https://www.ncbi.nlm.nih.gov/pubmed/33274002
http://dx.doi.org/10.1155/2020/5021694