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eys(+/-); lrp5(+/−) Zebrafish Reveals Lrp5 Can Be the Receptor of Retinol in the Visual Cycle

Vision is essential for vertebrates including humans. Sustained vision is accomplished by retinoid metabolism, the “visual cycle,” where all-trans retinol (atROL) is incorporated into the retinal pigment epithelium (RPE) from photoreceptors presumably through decade-long missing receptor(s). Here, w...

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Detalles Bibliográficos
Autores principales: Takita, Shimpei, Seko, Yuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683268/
https://www.ncbi.nlm.nih.gov/pubmed/33251495
http://dx.doi.org/10.1016/j.isci.2020.101762