Transient rho-associated coiled-coil containing kinase (ROCK) inhibition on human retinal pigment epithelium results in persistent Rho/ROCK downregulation

Retinal pigment epithelium (RPE) cells is the outermost layer of the retina and RPE dysfunction is a key factor in the disease pathogenesis of age-related macular degeneration (AMD). Transplantation therapy using induced pluripotent stem cell (iPSC)-derived RPEs has recently received much attention...

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Detalles Bibliográficos
Autores principales: Kitahata, Shohei, Ichikawa, Hinako, Tanaka, Yuji, Inoue, Tatsuya, Kadonosono, Kazuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683314/
https://www.ncbi.nlm.nih.gov/pubmed/33294632
http://dx.doi.org/10.1016/j.bbrep.2020.100841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683314/
https://www.ncbi.nlm.nih.gov/pubmed/33294632
http://dx.doi.org/10.1016/j.bbrep.2020.100841

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