Epidermal Growth Factor Receptor Inhibition Reverses Cellular and Transcriptomic Alterations Induced by Hypoxia in the Neonatal Piglet Brain

Acute hypoxia (HX) causes extensive cellular damage in the developing human cerebral cortex. We found increased expression of activated-EGFR in affected cortical areas of neonates with HX and investigated its functional role in the piglet, which displays a highly evolved, gyrencephalic brain, with a...

Descripción completa

Detalles Bibliográficos
Autores principales: Kratimenos, Panagiotis, Goldstein, Evan Z., Koutroulis, Ioannis, Knoblach, Susan, Jablonska, Beata, Banerjee, Payal, Malaeb, Shadi N., Bhattacharya, Surajit, Almira-Suarez, M. Isabel, Gallo, Vittorio, Delivoria-Papadopoulos, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683340/
https://www.ncbi.nlm.nih.gov/pubmed/33294779
http://dx.doi.org/10.1016/j.isci.2020.101766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683340/
https://www.ncbi.nlm.nih.gov/pubmed/33294779
http://dx.doi.org/10.1016/j.isci.2020.101766

Ejemplares similares