Autocrine negative feedback regulation of lipolysis through sensing of NEFAs by FFAR4/GPR120 in WAT

OBJECTIVES: Long-chain fatty acids (LCFAs) released from adipocytes inhibit lipolysis through an unclear mechanism. We hypothesized that the LCFA receptor, FFAR4 (GPR120), which is highly expressed in adipocytes, may be involved in this feedback regulation. METHODS AND RESULTS: Liquid chromatography...

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Detalles Bibliográficos
Autores principales: Husted, Anna Sofie, Ekberg, Jeppe H., Tripp, Emma, Nissen, Tinne A.D., Meijnikman, Stijn, O'Brien, Shannon L., Ulven, Trond, Acherman, Yair, Bruin, Sjoerd C., Nieuwdorp, Max, Gerhart-Hines, Zach, Calebiro, Davide, Dragsted, Lars O., Schwartz, Thue W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683346/
https://www.ncbi.nlm.nih.gov/pubmed/33091626
http://dx.doi.org/10.1016/j.molmet.2020.101103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683346/
https://www.ncbi.nlm.nih.gov/pubmed/33091626
http://dx.doi.org/10.1016/j.molmet.2020.101103

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