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Na(+)-NQR Confers Aminoglycoside Resistance via the Regulation of l-Alanine Metabolism

Sodium-translocating NADH:quinone oxidoreductase (Na(+)-NQR) functions as a unique redox-driven sodium pump, generating membrane potential, which is related to aminoglycoside antibiotic resistance. However, whether it modulates other metabolisms to confer antibiotic resistance is unknown. The presen...

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Detalles Bibliográficos
Autores principales: Jiang, Ming, Kuang, Su-fang, Lai, Shi-shi, Zhang, Song, Yang, Jun, Peng, Bo, Peng, Xuan-xian, Chen, Zhuang-gui, Li, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683393/
https://www.ncbi.nlm.nih.gov/pubmed/33203750
http://dx.doi.org/10.1128/mBio.02086-20