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NMR in target driven drug discovery: why not?

No matter the source of compounds, drug discovery campaigns focused directly on the target are entirely dependent on a consistent stream of reliable data that reports on how a putative ligand interacts with the protein of interest. The data will derive from many sources including enzyme assays and m...

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Detalles Bibliográficos
Autores principales: Keiffer, Sébastien, Carneiro, Marta G., Hollander, Johan, Kobayashi, Masakazu, Pogoryelev, Denys, AB, Eiso, Theisgen, Stephan, Müller, Gerhard, Siegal, Gregg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683447/
https://www.ncbi.nlm.nih.gov/pubmed/32901320
http://dx.doi.org/10.1007/s10858-020-00343-9