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Gut Microbiota and Bacterial DNA Suppress Autoimmunity by Stimulating Regulatory B Cells in a Murine Model of Lupus

Autoimmune diseases, such as systemic lupus erythematosus, are characterized by excessive inflammation in response to self-antigens. Loss of appropriate immunoregulatory mechanisms contribute to disease exacerbation. We previously showed the suppressive effect of vancomycin treatment during the “act...

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Detalles Bibliográficos
Autores principales: Mu, Qinghui, Edwards, Michael R., Swartwout, Brianna K., Cabana Puig, Xavier, Mao, Jiangdi, Zhu, Jing, Grieco, Joe, Cecere, Thomas E., Prakash, Meeta, Reilly, Christopher M., Puglisi, Christopher, Bachali, Prathyusha, Grammer, Amrie C., Lipsky, Peter E., Luo, Xin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683516/
https://www.ncbi.nlm.nih.gov/pubmed/33240280
http://dx.doi.org/10.3389/fimmu.2020.593353