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LncRNA lncLy6C induced by microbiota metabolite butyrate promotes differentiation of Ly6C(high) to Ly6C(int/neg) macrophages through lncLy6C/C/EBPβ/Nr4A1 axis

Macrophages are mainly divided into two populations, which play a different role in physiological and pathological conditions. The differentiation of these cells may be regulated by transcription factors. However, it is unclear how to modulate these transcription factors to affect differentiation of...

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Detalles Bibliográficos
Autores principales: Gao, Yunhuan, Zhou, Jiang, Qi, Houbao, Wei, Jianmei, Yang, Yazheng, Yue, Jianmei, Liu, Xinqi, Zhang, Yuan, Yang, Rongcun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683537/
https://www.ncbi.nlm.nih.gov/pubmed/33298871
http://dx.doi.org/10.1038/s41421-020-00211-8