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LncRNA lncLy6C induced by microbiota metabolite butyrate promotes differentiation of Ly6C(high) to Ly6C(int/neg) macrophages through lncLy6C/C/EBPβ/Nr4A1 axis
Macrophages are mainly divided into two populations, which play a different role in physiological and pathological conditions. The differentiation of these cells may be regulated by transcription factors. However, it is unclear how to modulate these transcription factors to affect differentiation of...
Autores principales: | Gao, Yunhuan, Zhou, Jiang, Qi, Houbao, Wei, Jianmei, Yang, Yazheng, Yue, Jianmei, Liu, Xinqi, Zhang, Yuan, Yang, Rongcun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683537/ https://www.ncbi.nlm.nih.gov/pubmed/33298871 http://dx.doi.org/10.1038/s41421-020-00211-8 |
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