Small molecule modulation of the p75 neurotrophin receptor inhibits multiple amyloid beta-induced tau pathologies

Longitudinal preclinical and clinical studies suggest that Aβ drives neurite and synapse degeneration through an array of tau-dependent and independent mechanisms. The intracellular signaling networks regulated by the p75 neurotrophin receptor (p75(NTR)) substantially overlap with those linked to Aβ...

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Detalles Bibliográficos
Autores principales: Yang, Tao, Tran, Kevin C., Zeng, Anne Y., Massa, Stephen M., Longo, Frank M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683564/
https://www.ncbi.nlm.nih.gov/pubmed/33230162
http://dx.doi.org/10.1038/s41598-020-77210-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683564/
https://www.ncbi.nlm.nih.gov/pubmed/33230162
http://dx.doi.org/10.1038/s41598-020-77210-y

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