(89)Zr-pro-MMP-9 F(ab′)(2) detects colitis induced intestinal and kidney fibrosis

Intestinal fibrosis is a common complication of inflammatory bowel disease but remains difficult to detect. Matrix metalloproteases (MMPs) have key roles in fibrosis and are therefore potential targets for fibrosis detection. We determined whether immunoPET of F(ab′)(2) antibody fragments targeting...

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Detalles Bibliográficos
Autores principales: Dmochowska, Nicole, Tieu, William, Keller, Marianne D., Hollis, Courtney A., Campaniello, Melissa A., Mavrangelos, Chris, Takhar, Prab, Hughes, Patrick A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683569/
https://www.ncbi.nlm.nih.gov/pubmed/33230169
http://dx.doi.org/10.1038/s41598-020-77390-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683569/
https://www.ncbi.nlm.nih.gov/pubmed/33230169
http://dx.doi.org/10.1038/s41598-020-77390-7

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