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(89)Zr-pro-MMP-9 F(ab′)(2) detects colitis induced intestinal and kidney fibrosis
Intestinal fibrosis is a common complication of inflammatory bowel disease but remains difficult to detect. Matrix metalloproteases (MMPs) have key roles in fibrosis and are therefore potential targets for fibrosis detection. We determined whether immunoPET of F(ab′)(2) antibody fragments targeting...
Autores principales: | Dmochowska, Nicole, Tieu, William, Keller, Marianne D., Hollis, Courtney A., Campaniello, Melissa A., Mavrangelos, Chris, Takhar, Prab, Hughes, Patrick A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683569/ https://www.ncbi.nlm.nih.gov/pubmed/33230169 http://dx.doi.org/10.1038/s41598-020-77390-7 |
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