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ProTECT—Prediction of T-Cell Epitopes for Cancer Therapy

Somatic mutations in cancers affecting protein coding genes can give rise to potentially therapeutic neoepitopes. These neoepitopes can guide Adoptive Cell Therapies and Peptide- and RNA-based Neoepitope Vaccines to selectively target tumor cells using autologous patient cytotoxic T-cells. Currently...

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Detalles Bibliográficos
Autores principales: Rao, Arjun A., Madejska, Ada A., Pfeil, Jacob, Paten, Benedict, Salama, Sofie R., Haussler, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683782/
https://www.ncbi.nlm.nih.gov/pubmed/33244314
http://dx.doi.org/10.3389/fimmu.2020.483296