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miRNA-486-5p Promotes COPD Progression by Targeting HAT1 to Regulate the TLR4-Triggered Inflammatory Response of Alveolar Macrophages

PURPOSE: The aim of this study was to investigate the role of miRNA-486-5p in chronic obstructive pulmonary disease (COPD) progression and the underlying molecular mechanisms. MATERIALS AND METHODS: Aberrant miRNA expression profiles between smokers and nonsmokers, and those between COPD patients an...

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Detalles Bibliográficos
Autores principales: Zhang, Jie, Xu, Zhongneng, Kong, Lianhua, Gao, Hong, Zhang, Yueming, Zheng, Yulong, Wan, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683830/
https://www.ncbi.nlm.nih.gov/pubmed/33244226
http://dx.doi.org/10.2147/COPD.S280614