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Circadian Clock Protein PERIOD2 Suppresses the PI3K/Akt Pathway and Promotes Cisplatin Sensitivity in Ovarian Cancer

BACKGROUND: The mortality rate of ovarian cancer is the highest among gynecological tumors. The two factors leading to high mortality of ovarian cancer are late clinical stage and chemotherapy resistance. It is very important to reverse or intervene chemotherapy resistance. Abnormal circadian rhythm...

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Detalles Bibliográficos
Autores principales: Wang, Zhaoxia, Li, Fengyan, Wei, Meiyan, Zhang, Sanyuan, Wang, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683831/
https://www.ncbi.nlm.nih.gov/pubmed/33244267
http://dx.doi.org/10.2147/CMAR.S278903