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Structural basis for assembly of non-canonical small subunits into type I-C Cascade

Bacteria and archaea employ CRISPR (clustered, regularly, interspaced, short palindromic repeats)-Cas (CRISPR-associated) systems as a type of adaptive immunity to target and degrade foreign nucleic acids. While a myriad of CRISPR-Cas systems have been identified to date, type I-C is one of the most...

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Detalles Bibliográficos
Autores principales: O’Brien, Roisin E., Santos, Inês C., Wrapp, Daniel, Bravo, Jack P. K., Schwartz, Evan A., Brodbelt, Jennifer S., Taylor, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7684278/
https://www.ncbi.nlm.nih.gov/pubmed/33230133
http://dx.doi.org/10.1038/s41467-020-19785-8