Structural insight into the assembly and conformational activation of human origin recognition complex

The function of the origin recognition complex (ORC) in DNA replication is highly conserved in recognizing and marking the initiation sites. The detailed molecular mechanisms by which human ORC is reconfigured into a state competent for origin association remain largely unknown. Here, we present str...

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Detalles Bibliográficos
Autores principales: Cheng, Jiaxuan, Li, Ningning, Wang, Xiaohan, Hu, Jiazhi, Zhai, Yuanliang, Gao, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7684300/
https://www.ncbi.nlm.nih.gov/pubmed/33298899
http://dx.doi.org/10.1038/s41421-020-00232-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7684300/
https://www.ncbi.nlm.nih.gov/pubmed/33298899
http://dx.doi.org/10.1038/s41421-020-00232-3

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