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Insights in the regulation of trimetylamine N-oxide production using a comparative biomimetic approach suggest a metabolic switch in hibernating bears

Experimental studies suggest involvement of trimethylamine N-oxide (TMAO) in the aetiology of cardiometabolic diseases and chronic kidney disease (CKD), in part via metabolism of ingested food. Using a comparative biomimetic approach, we have investigated circulating levels of the gut metabolites be...

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Detalles Bibliográficos
Autores principales: Ebert, Thomas, Painer, Johanna, Bergman, Peter, Qureshi, Abdul Rashid, Giroud, Sylvain, Stalder, Gabrielle, Kublickiene, Karolina, Göritz, Frank, Vetter, Sebastian, Bieber, Claudia, Fröbert, Ole, Arnemo, Jon M., Zedrosser, Andreas, Redtenbacher, Irene, Shiels, Paul G., Johnson, Richard J., Stenvinkel, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7684304/
https://www.ncbi.nlm.nih.gov/pubmed/33230252
http://dx.doi.org/10.1038/s41598-020-76346-1