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Transgenerational effect of drug-mediated inhibition of LSD1 on eye pigment expression in Drosophila

BACKGROUND: The Drosophila melanogaster mutant white-mottled is a well-established model for position-effect variegation (PEV). Transposition of the euchromatic white gene into the vicinity of the pericentric heterochromatin caused variegated expression of white due to heterochromatin spreading. The...

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Detalles Bibliográficos
Autor principal: Hoyer-Fender, Sigrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7684728/
https://www.ncbi.nlm.nih.gov/pubmed/33228645
http://dx.doi.org/10.1186/s12898-020-00330-6