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Transcription factor EB agonists from natural products for treating human diseases with impaired autophagy-lysosome pathway

Autophagy is a highly conserved degradation process for long-lived intracellular proteins and organelles mediated by lysosomes. Deficits in the autophagy-lysosome pathway (ALP) have been linked to a variety of human diseases, including neurodegenerative diseases, lysosomal storage disorders, and can...

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Detalles Bibliográficos
Autores principales: Xu, Jie, Zhang, Xiao-Qi, Zhang, Zaijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7684757/
https://www.ncbi.nlm.nih.gov/pubmed/33292395
http://dx.doi.org/10.1186/s13020-020-00402-1