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Dexmedetomidine for the prevention of postoperative delirium in patients after intracranial operation for brain tumours (DEPOD study): a study protocol and statistical plan for a multicentre randomised controlled trial

INTRODUCTION: Postoperative delirium (POD) is prevalent in patients after major surgery and is associated with adverse outcomes. Several studies have reported that dexmedetomidine, a highly selective α2-adrenergic receptor agonist, can decrease the incidence of POD. However, neurosurgical patients a...

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Detalles Bibliográficos
Autores principales: He, Xuan, Cheng, Kun-Ming, Zhang, Linlin, Gu, Hongqiu, Qu, Xin, Xu, Yuan, Ma, Penglin, Zhou, Jian-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7684814/
https://www.ncbi.nlm.nih.gov/pubmed/33234648
http://dx.doi.org/10.1136/bmjopen-2020-040939