Molecular characteristics of BRCA1/2 and PALB2 mutations in pancreatic ductal adenocarcinoma
INTRODUCTION: Poly-(ADP)-ribose polymerase (PARP) inhibitors are successfully used for treatment of BRCA-mutated (mut) breast cancers and are under extensive evaluation for BRCA- and PALB2-mutated pancreatic ductal adenocarcinoma (PDAC). However, the optimal treatment regimen for BRCA/PALB2-mutated...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7684832/ https://www.ncbi.nlm.nih.gov/pubmed/33229504 http://dx.doi.org/10.1136/esmoopen-2020-000942 |