Mesenchymal stem cells negatively regulate CD4(+) T cell activation in patients with primary Sjögren syndrome through the miRNA-125b and miRNA-155 TCR pathway

Treatment with mesenchymal stem cells (MSCs) has been revealed to suppress CD4(+) T cells and autoimmunity in both mouse models and patients with primary Sjögren syndrome (pSS); however, the underlying mechanism remains unclear. MicroRNAs (miRNAs or miRs) mediate CD4(+) T cell activation, but the me...

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Detalles Bibliográficos
Autores principales: Gong, Bangdong, Zheng, Ling, Lu, Zhenhao, Huang, Jiashu, Pu, Jincheng, Pan, Shengnan, Zhang, Min, Liu, Jie, Tang, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7684863/
https://www.ncbi.nlm.nih.gov/pubmed/33179091
http://dx.doi.org/10.3892/mmr.2020.11681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7684863/
https://www.ncbi.nlm.nih.gov/pubmed/33179091
http://dx.doi.org/10.3892/mmr.2020.11681

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