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Tanshinone I and simvastatin inhibit melanoma tumour cell growth by regulating poly (ADP ribose) polymerase 1 expression

Melanoma is one of the most aggressive forms of skin tumour with poor prognosis; no effective therapy has been established for melanoma at the metastatic stage. The present study aimed to investigate the role of poly (ADP ribose) polymerase (PARP) inhibitors (PARPis) and PARP1 expression in melanoma...

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Detalles Bibliográficos
Autores principales: Zhang, Yuyan, Huang, Jiusui, Huang, Yapeng, Zhang, Shike, Wu, Weizhou, Long, Hui, Duan, Xiaolu, Lai, Yongchang, Wu, Wenqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7684874/
https://www.ncbi.nlm.nih.gov/pubmed/33179075
http://dx.doi.org/10.3892/mmr.2020.11678