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Mixed logistic regression in genome-wide association studies
BACKGROUND: Mixed linear models (MLM) have been widely used to account for population structure in case-control genome-wide association studies, the status being analyzed as a quantitative phenotype. Chen et al. proved in 2016 that this method is inappropriate in some situations and proposed GMMAT,...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7684894/ https://www.ncbi.nlm.nih.gov/pubmed/33228527 http://dx.doi.org/10.1186/s12859-020-03862-2 |