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Monocyte Chemoattractant Protein-1 promotes cancer cell migration via c-Raf/MAPK/AP-1 pathway and MMP-9 production in osteosarcoma

BACKGROUND: Osteosarcoma is generally reported among younger individuals and has a very poor prognosis, particularly for the development of metastasis. However, more effective metastatic biomarkers and therapeutic methods are absent. Monocyte chemoattractant protein-1 (MCP-1) is involved in cancer p...

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Detalles Bibliográficos
Autores principales: Liu, Ju-Fang, Chen, Po-Chun, Chang, Tsung-Ming, Hou, Chun-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7684958/
https://www.ncbi.nlm.nih.gov/pubmed/33228783
http://dx.doi.org/10.1186/s13046-020-01756-y