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BDCA1(+) cDC2s, BDCA2(+) pDCs and BDCA3(+) cDC1s reveal distinct pathophysiologic features and impact on clinical outcomes in melanoma patients

OBJECTIVES: Dendritic cells play a pivotal but still enigmatic role in the control of tumor development. Composed of specialised subsets (cDC1s, cDC2s, pDCs), DCs are critical in triggering and shaping antitumor immune responses. Yet, tumors exploit plasticity of DCs to subvert their functions and e...

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Detalles Bibliográficos
Autores principales: Sosa Cuevas, Eleonora, Ouaguia, Laurissa, Mouret, Stephane, Charles, Julie, De Fraipont, Florence, Manches, Olivier, Valladeau‐Guilemond, Jenny, Bendriss‐Vermare, Nathalie, Chaperot, Laurence, Aspord, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7684973/
https://www.ncbi.nlm.nih.gov/pubmed/33282290
http://dx.doi.org/10.1002/cti2.1190