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A population of CD4(hi)CD38(hi) T cells correlates with disease severity in patients with acute malaria

OBJECTIVE: CD4(+) T cells are critical mediators of immunity to Plasmodium spp. infection, but their characteristics during malarial episodes and immunopathology in naturally infected adults are poorly defined. Flow cytometric analysis of PBMCs from patients with either P. falciparum or P. knowlesi...

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Detalles Bibliográficos
Autores principales: Apte, Simon H, Minigo, Gabriela, Groves, Penny L, Spargo, Jessie C, Plebanski, Magdalena, Grigg, Mathew J, Kenangalem, Enny, Burel, Julie G, Loughland, Jessica R, Flanagan, Katie L, Piera, Kim A, William, Timothy, Price, Ric N, Woodberry, Tonia, Barber, Bridget E, Anstey, Nicholas M, Doolan, Denise L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7684974/
https://www.ncbi.nlm.nih.gov/pubmed/33282291
http://dx.doi.org/10.1002/cti2.1209