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A population of CD4(hi)CD38(hi) T cells correlates with disease severity in patients with acute malaria
OBJECTIVE: CD4(+) T cells are critical mediators of immunity to Plasmodium spp. infection, but their characteristics during malarial episodes and immunopathology in naturally infected adults are poorly defined. Flow cytometric analysis of PBMCs from patients with either P. falciparum or P. knowlesi...
Autores principales: | Apte, Simon H, Minigo, Gabriela, Groves, Penny L, Spargo, Jessie C, Plebanski, Magdalena, Grigg, Mathew J, Kenangalem, Enny, Burel, Julie G, Loughland, Jessica R, Flanagan, Katie L, Piera, Kim A, William, Timothy, Price, Ric N, Woodberry, Tonia, Barber, Bridget E, Anstey, Nicholas M, Doolan, Denise L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7684974/ https://www.ncbi.nlm.nih.gov/pubmed/33282291 http://dx.doi.org/10.1002/cti2.1209 |
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