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Manganese Exposure Aggravates β-Amyloid Pathology by Microglial Activation

Human epidemiological evidence and animal experimental data suggest that chronic manganese (Mn) exposure increases the risk of Alzheimer’s disease (AD) and amyloid plaques, a hallmark of AD brain pathology, but the underlying mechanisms were not fully understood. Using the transgenic APP/PS1/Tau tri...

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Detalles Bibliográficos
Autores principales: Lin, Geng, Li, Xinlu, Cheng, Xiaofeng, Zhao, Ning, Zheng, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685005/
https://www.ncbi.nlm.nih.gov/pubmed/33244298
http://dx.doi.org/10.3389/fnagi.2020.556008