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Manganese Exposure Aggravates β-Amyloid Pathology by Microglial Activation
Human epidemiological evidence and animal experimental data suggest that chronic manganese (Mn) exposure increases the risk of Alzheimer’s disease (AD) and amyloid plaques, a hallmark of AD brain pathology, but the underlying mechanisms were not fully understood. Using the transgenic APP/PS1/Tau tri...
Autores principales: | Lin, Geng, Li, Xinlu, Cheng, Xiaofeng, Zhao, Ning, Zheng, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685005/ https://www.ncbi.nlm.nih.gov/pubmed/33244298 http://dx.doi.org/10.3389/fnagi.2020.556008 |
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