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Icariin inhibits the inflammation through down-regulating NF-κB/HIF-2α signal pathways in chondrocytes

Articular cartilage injury or defect is a common disease and is mainly characterized by cartilage degradation because of chondrocyte inflammation. By now, there are no effective drugs and methods to protect articular cartilage from degradation. Icariin (ICA) is a typical flavonoid compound extracted...

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Detalles Bibliográficos
Autores principales: Wang, Pengzhen, Meng, Qingqi, Wang, Wen, Zhang, Shaoheng, Xiong, Xifeng, Qin, Shengnan, Zhang, Jinli, Li, Aiguo, Liu, Zhihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685011/
https://www.ncbi.nlm.nih.gov/pubmed/33155655
http://dx.doi.org/10.1042/BSR20203107