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Improved computational analysis of ribosome dynamics from 5′P degradome data using fivepseq

In eukaryotes, 5′–3′ co-translation degradation machinery follows the last translating ribosome providing an in vivo footprint of its position. Thus, 5′ monophosphorylated (5′P) degradome sequencing, in addition to informing about RNA decay, also provides information regarding ribosome dynamics. Mul...

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Detalles Bibliográficos
Autores principales: Nersisyan, Lilit, Ropat, Maria, Pelechano, Vicent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685019/
https://www.ncbi.nlm.nih.gov/pubmed/33575643
http://dx.doi.org/10.1093/nargab/lqaa099