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High levels of maternal total tri-iodothyronine, and low levels of fetal free L-thyroxine and total tri-iodothyronine, are associated with altered deiodinase expression and activity in placenta with gestational diabetes mellitus

Gestational Diabetes Mellitus (GDM) is characterized by abnormal maternal D-glucose metabolism and altered insulin signaling. Dysregulation of thyroid hormones (TH) tri-iodethyronine (T(3)) and L-thyroxine (T(4)) Hormones had been associated with GDM, but the physiopathological meaning of these alte...

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Detalles Bibliográficos
Autores principales: Gutiérrez-Vega, Sebastián, Armella, Axel, Mennickent, Daniela, Loyola, Marco, Covarrubias, Ambart, Ortega-Contreras, Bernel, Escudero, Carlos, Gonzalez, Marcelo, Alcalá, Martín, Ramos, María del Pilar, Viana, Marta, Castro, Erica, Leiva, Andrea, Guzmán-Gutiérrez, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685482/
https://www.ncbi.nlm.nih.gov/pubmed/33232364
http://dx.doi.org/10.1371/journal.pone.0242743