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High levels of maternal total tri-iodothyronine, and low levels of fetal free L-thyroxine and total tri-iodothyronine, are associated with altered deiodinase expression and activity in placenta with gestational diabetes mellitus
Gestational Diabetes Mellitus (GDM) is characterized by abnormal maternal D-glucose metabolism and altered insulin signaling. Dysregulation of thyroid hormones (TH) tri-iodethyronine (T(3)) and L-thyroxine (T(4)) Hormones had been associated with GDM, but the physiopathological meaning of these alte...
Autores principales: | Gutiérrez-Vega, Sebastián, Armella, Axel, Mennickent, Daniela, Loyola, Marco, Covarrubias, Ambart, Ortega-Contreras, Bernel, Escudero, Carlos, Gonzalez, Marcelo, Alcalá, Martín, Ramos, María del Pilar, Viana, Marta, Castro, Erica, Leiva, Andrea, Guzmán-Gutiérrez, Enrique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685482/ https://www.ncbi.nlm.nih.gov/pubmed/33232364 http://dx.doi.org/10.1371/journal.pone.0242743 |
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