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Aquaporin-3 regulates endosome-to-cytosol transfer via lipid peroxidation for cross presentation
Antigen cross presentation, whereby exogenous antigens are presented by MHC class I molecules to CD8+ T cells, is essential for generating adaptive immunity to pathogens and tumor cells. Following endocytosis, it is widely understood that protein antigens must be transferred from endosomes to the cy...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685505/ https://www.ncbi.nlm.nih.gov/pubmed/33232321 http://dx.doi.org/10.1371/journal.pone.0238484 |