CCL2 facilitates spinal synaptic transmission and pain via interaction with presynaptic CCR2 in spinal nociceptor terminals

Previous studies have shown that CCL2 may cause chronic pain, but the exact mechanism of central sensitization is unclear. In this article, we further explore the presynaptic role of CCL2. Behavioral experiments show that intervertebral foramen injection CCR2 antagonists into dorsal root ganglion (D...

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Detalles Bibliográficos
Autores principales: Ma, Sui-Bin, Xian, Hang, Wu, Wen-Bin, Ma, Shuo-Yao, Liu, Yu-Ke, Liang, Yu-Tong, Guo, Huan, Kang, Jun-Jun, Liu, Ying-Ying, Zhang, Hui, Wu, Sheng-Xi, Luo, Ceng, Xie, Rou-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685578/
https://www.ncbi.nlm.nih.gov/pubmed/33228784
http://dx.doi.org/10.1186/s13041-020-00701-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7685578/
https://www.ncbi.nlm.nih.gov/pubmed/33228784
http://dx.doi.org/10.1186/s13041-020-00701-6

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